Which statement correctly pairs an ADR type with its example?

Which statement correctly pairs an ADR type with its example?

• A. Type E ADR — Opiate withdrawal
• B. Type F ADR — End of use
• C. Type E ADR — Resistance to antimicrobial agents
• D. Type E ADR — Withdrawal reaction, End of use

Answer: (D)

Type E adverse drug reactions are withdrawal effects that appear when a drug is stopped or its use ends. They arise from physiological dependence and rebound phenomena. The best match describes a withdrawal reaction occurring at the end of use, which is exactly what this ADR type encompasses. The other options misalign either the type or the example: pairing end of use with therapy failure does not describe withdrawal, and linking resistance to antimicrobial agents isn’t a withdrawal phenomenon. While an opiate withdrawal is a withdrawal example, the canonical description of this ADR type is a withdrawal reaction at end of use, so this pairing is the most accurate.

Type E adverse drug reactions are withdrawal effects that appear when a drug is stopped or its use ends. They arise from physiological dependence and rebound phenomena. The best match describes a withdrawal reaction occurring at the end of use, which is exactly what this ADR type encompasses. The other options misalign either the type or the example: pairing end of use with therapy failure does not describe withdrawal, and linking resistance to antimicrobial agents isn’t a withdrawal phenomenon. While an opiate withdrawal is a withdrawal example, the canonical description of this ADR type is a withdrawal reaction at end of use, so this pairing is the most accurate.